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atterns are frequently large-sized fragments that involve the acetabular roof and are rendered stable after reconstruction of the columns. The malignant transformation of normal bladder cells (SV-HUC-1) was induced by arsenite to explore the possible mechanism of circRNA-100284 influencing bladder cancer cell proliferation. Normal bladder SV-HUC-1 cells were cultured with 2μM arsenite to induce malignant transformation. After 0, 3, 6, 12, and 24h of culture, the expression level of circRNA-100284 in cells was detected by quantitative real