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How to Choose the Best ADHD Medication for Adults The stimulant drugs like methylphenidate and amphetamine function by increasing and balancing brain chemicals. Doctors often prescribe them as pills, liquids or patches. ADHD can also be treated by healthcare professionals using medications known as alpha-2 agonists and norepinephrine-reuptake inhibitors. They are typically used "off-label" to treat this condition as they're FDA-approved to treat other conditions. Stimulants Stimulants are th