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cluded that using multiple CSTRs that are operated at low SRTs in a cascade mode of operation significantly improved the enzymatic hydrolysis rate and extend in anaerobic WAS digestion. Moreover, the governing hydrolysis kinetics in the cascading reactors were far more complex than the generally assumed simplified first-order kinetics.Bromine (Br) and iodine (I) in source water can form highly toxic brominated or iodinated disinfection byproducts in treatment plants. For the first time, the occurrence of Br and I speciation and their p