https://www.selleckchem.com/pr....oducts/Dihydromyrice
BACKGROUND AND OBJECTIVES Alloimmunization targeting major histocompatibility (MHC) antigens is common following platelet transfusion. Pathogen reduction of platelets can block alloimmunization to MHC in mice and induce partial antigen-specific tolerance to subsequent transfusions. This study utilized small allelic variants to evaluate the relative contributions of class I and class II MHC to the alloresponse against untreated or pathogen-reduced platelets. MATERIALS AND METHODS C57BL/6 (B6) Kbm1 and B6 IAbm12 mice w
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