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The Most Effective ADHD Medication For Adults The majority of ADHD medications are classified into two categories: stimulants and nonstimulants. The stimulants such as methylphenidate (Provigil) and amphetamines act by increasing the activity in areas of the brain responsible for the behavior and attention. Non-stimulants like atomoxetine (Strattera) and Guanfacine (Intuniv) and Clonidine (Kapvay), work slower than stimulants but help improve concentration, focus and impulsivity. They also appear to d
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