https://www.selleckchem.com/pr....oducts/h-cys-trt-oh.
Despite lacking the α-helical structures in Cry1A that are responsible for pore formation, ingestion of GEAb-dV disrupted the P. xylostella larval midgut epithelium and resulted in toxicity. Apoptotic genes were activated in gut cells upon treatment with GEAb-dV . This study describes the first insecticidal GEAb targeting P. xylostella by mimicking Cry proteins. Data support that GEAb-dV toxicity is associated to activation of intracellular cell death pathways, in contrast to pore-formation associated toxicity of Cry proteins. This
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