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A recent single-cell RNA sequencing study by Wilk . suggested that plasmablasts can transdifferentiate into 'developing neutrophils' in patients with severe COVID-19 disease. We explore the evidence for this. We downloaded the original data and code used by the authors in their study to replicate their findings and explore the possibility that regressing out variables may have led the authors to overfit their data. The lineage relationship between plasmablasts and developing neutrophils breaks down when key features are not regressed ou