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We conclude that long-chain enrichment is central to the mechanism of flow-induced nucleation and that this enrichment must be captured to correctly predict the nucleation rate.A number of clinical trials have examined the effect of almond intake on lipid profile in recent years; however, the results remain equivocal. Therefore, the present study aims to summarize and quantitatively examine the available evidence on the effectiveness of almond intake on lipid parameters by employing a systematic review and meta-analytic approach. Online