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https://www.selleckchem.com/pr....oducts/l-685-458.htm
Only neonatal mice exhibited an increase in BMP4 protein expression whereas adult kidneys strongly upregulated phosphatidylinositol 3 kinase class III, essential for compensatory hypertrophy. In conclusion, gene regulation differs in neonatal and adult mice with UUO. Repair and compensatory hypertrophy involve different genetic programs in developing and adult obstructed kidneys.Bioinspired smart materials represent a tremendously growing research field and the obtainment of new building blocks is at the molecular basis of this techno