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The word "fixel" refers to the specific fiber population within each voxel, and fixel-based analysis (FBA) is a recently developed technique that facilitates fiber tract-specific statistical analysis. The aim of the paper is to apply FBA to detect impaired fibers for corticobasal syndrome (CBS) especially in regions that contain multiple crossed fibers. FBA was performed in cohorts of participants clinically diagnosed with CBS (n = 1 and Parkinson's disease (n = 15) or in healthy controls (n = 9). The parameters of the diffusion weight