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The Most Effective ADHD Medication For Adults Most ADHD medications fall into two categories: stimulants and nonstimulants. The stimulants such as methylphenidate (Provigil) and amphetamines function by increasing activity in parts of the brain that regulate attention and behaviour. Non-stimulants like guanfacine atomoxetine, and clonidine, perform slower than stimulants but they help improve focus and attention as well as impulsivity. They also appear to decrease anx
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