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Natural ADHD Medication Alternatives There are a myriad of supplements and natural remedies that claim to treat ADHD. These remedies are not controlled by the FDA and may cause adverse effects or interact with other medications. Pycnogenol is a plant extract that has shown promise in relieving ADHD symptoms in some studies. It is believed to boost the cognitive function and decrease restlessness. Nootropics Many people with ADHD who have been diagnosed have found that holistic treatments, such as talking therapy and lifestyle changes, can help relieve their sympt