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12, 0.12 and 0.21 respectively; OAI SD=0.08, 0.08 and 0.11 respectively). Estimates from LME and Bayesian modelling were statistically significant predictors of change in pain in SEKOIA (LME P-value=0.04, Bayes P-value=0.04), while crude change did not predict change in pain (P-value=0.1. Implementation of LME or Bayesian modelling in clinical trials and epidemiological studies, would reduce sample sizes by enabling all study participants to be included in analysis regardless of incomplete follow up, and precision of change estimates
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