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The current study ended up being performed to investigate the effects of maternal therapy with pentaerythritol tetranitrate (PETN) in Dahl salt-sensitive rats (DSSR), a model of superimposed preeclampsia. F0 parental DSSR were treated with PETN (50 mg/kg) from the time point of mating to the end of lactation. Maternal PETN treatment improved fetal growth and had no impact on blood pressure levels in DSSR offspring given with typical chow or high-salt diet. Upon high-fat diet (HFD) feeding, offspring from PETN-tre