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The Most Effective ADHD Medication For Adults The majority of ADHD medications are classified into two categories: stimulants or non-stimulants. The stimulants, like methylphenidate or amphetamines boost brain activity areas that control attention and behavior. Non-stimulants, like atomoxetine (Strattera), Guanfacine (Intuniv) and clonidine (Kapvay) are slower than stimulants but can help increase focus, concentration and impulsivity. They also appear to decre