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Necrotizing soft tissue infections (NSTI) are an acute surgical condition with high morbidity and mortality. Timely identification, resuscitation and aggressive surgical management has significantly decreased inpatient mortality. However, reduced inpatient mortality has shifted the burden of disease to long-term mortality associated with persistent organ dysfunction. We performed a combined analysis of NSTI patients from the ACCUTE randomized-controlled interventional trial (ATB-202) and comprehensive administrative database (ATB-204) in
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