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The results of the present study suggest that supplementation of vitamin D3 has no additional benefit over placebo on pancreatic β-cell functions in non-diabetic Indian subjects with obesity. Further larger studies are required to confirm the results of the study. The trial is registered with the Clinical Trials Registry of India, CTRI/2015/04/005727. To simulate the process of curve correction with different strategies of pedicle screws placement, and then explore the ideal strategy. A three-dimensional model was constructed using CT dat