https://www.selleckchem.com/pr....oducts/seclidemstat.
Mean follow-up time was 6·7 (range 3·4-11· years after surgery. The prevalence of LARS was 77·4 per cent (370 of 478 patients), with 53·1 per cent (254 of 478) experiencing major LARS. Patients with major LARS reported worse on all EORTC QLQ-C30 subscales (except for financial difficulties) than patients without LARS. A higher mean LARS score was associated with a greater impact on bowel-related QoL. Conclusion After anterior resection for rectal cancer, the majority of patients suffer from major LARS with a negative impact on Qo
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