https://www.selleckchem.com/pr....oducts/pf-06700841.h
Human lung alveolar epithelial (A549) cells were exposed to PM1, revealing increases in lactate dehydrogenase (LDH), reactive oxygen species (ROS), and interlukin-6 (IL-6), which indicated the occurrence of inflammatory and oxidative responses. POA was significantly associated with ROS and IL-6, and alkanes, hopanes, steranes, PAHs and OPAHs, and fatty acids presented medium to high correlations with LDH and IL-6, demonstrating the importance of primary emissions and organic compounds in cytotoxicity. This study demonstrated that or
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