https://www.selleckchem.com/pr....oducts/R7935788-Fost
Malignant pleural mesothelioma (MPM) is a fatal tumor with a poor prognosis. The recent developments of liquid biopsies could provide novel diagnostic and prognostic tools in oncology. However, there is limited information about the feasibility of this technique for MPMs. Here, we investigate whether cancer-specific DNA sequences can be detected in pleural fluids and plasma of MPM patients as free circulating tumor DNA (ctDNA). We performed whole-exome sequencing on 14 tumor biopsies from 14 patients, and we analyzed 20 pa