https://www.selleckchem.com/pr....oducts/ganetespib-st
How to perform an intention to treat (ITT) analysis when a patient has a baseline value but no follow-up measurements is problematic. The purpose of this study was to compare different methods that deal with this problem, i.e. no imputation (standard and alternative mixed model analysis), single imputation (i.e. baseline value carried forward), and multiple imputation (selective and non-selective). We used a simulation study with different scenarios regarding 1) the association between missingness and the baseline value, 2)
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