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Finding the Best Medication For ADHD There are a variety of ADHD medications, and it could take time to identify the one that is most effective for you. It is essential to be honest with your physician about how ADHD affects you, so that they can determine the most effective medication for you. Stimulants, which are the most commonly used treatment for ADHD, can cause side effects such as anxiety and mood changes. Some people experience tics as well when taking stimulants. Methylphenidate Methylphenida