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The drug discovery pipeline for Chagas infection presently has few brand-new clinical applicants, with high attrition prices a continuing concern. To find out if the Trypanosoma cruzi stress used to evaluate in vitro mixture task impacts activity, an assessment of laboratory-adapted T. cruzi strains from varying geographical places had been undertaken for a selection of compounds with anti-T. cruzi activity. To minimise the feasible effect of differences in experimental methodo
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