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We anticipated that DNA4mC-LIP could serve as a powerful computational technique for identifying 4mC sites and facilitate the interpretation of 4mC mechanism. AVAILABILITY http//i.uestc.edu.cn/DNA4mC-LIP/. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online. © The Author(s) (202. Published by Oxford University Press. All rights reserved. For Permissions, please email journals.permissions@oup.com.BACKGROUND Conventional analytic approaches for studying diet patterns assume no dietary synergy, which c