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We found age-related changes in monocyte metabolic fitness, including reduced mitochondrial function and increased glycose consumption without the capacity to upregulate it during increased metabolic needs, and signs of increased oxidative stress and DNA damage. In conclusion, our results complement existing findings and elucidate the metabolic alterations that occur in monocytes during aging. © 2020 The Authors. Aging Cell published by the Anatomical Society and John Wiley Sons Ltd.This work reports development of yttrium doped co
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