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Among colon cancer patients, liver metastasis is a commonly deadly phenomenon, but there are few prognostic models for these patients. The clinicopathologic data of colon cancer with liver metastasis (CCLM) patients were downloaded from the Surveillance, Epidemiology and End Results (SEER) database. All patients were randomly divided into training and internal validation sets based on the ratio of 73. A prognostic nomogram was established with Cox analysis in the training set, which was validated by two independent validation sets. A tota