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03). The presence of ctDNA following local treatment of metastatic CRC is associated with an increased risk of recurrence and a short time to failure. The presence of ctDNA following local treatment of metastatic CRC is associated with an increased risk of recurrence and a short time to failure.The essential scope of the coronavirus infectious disease 2019 (COVID-19) pandemic is focused on developing effective treatments and vaccines for acute SARS-CoV-2 infection. There is also a critical need to develop interventions to prevent the comp