https://www.selleckchem.com/pr....oducts/bms-986278.ht
Alzheimer's Disease (AD) is the most frequent neurodegenerative disorder. Although proteinaceous aggregates of extracellular amyloid-β (Aβ) and intracellular hyperphosphorylated microtubuleassociated tau have long been identified as characteristic neuropathological hallmarks of AD, a diseasemodifying therapy against these targets has not been successful. An emerging concept is that microglia, the innate immune cells of the brain, are major players in AD pathogenesis. Microglia are long-lived tissue-resident professional phagocytes th
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