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Neonatal brain injury (NBI) is a serious adverse outcome in premature neonates. We sought to determine the levels and prognostic value of serum S100B during the first three days of life in premature neonates (34weeks) that later developed NBI in the form of either intraventricular hemorrhage (IVH) or periventricular leukomalacia (PVL). This is a prospective case - control longitudinal study. Each case (n=29) was matched according to birthweight and gestational age to one neonate with normal head ultrasound scans. Neonates with NBI,
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