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To methodically review nail abnormalities in clients with EB reported within the literature. We searched all published articles in electric databases until June 2020 reporting patients with EB with detailed descriptions of malformed/diseased nails making use of specific terms and inclusion/exclusion requirements. Medical data had been extracted by two separate writers. Descriptive statistics were used. We included 36 articles reporting 74 individual customers with a mean age of 28.23years 29 (39.2%) had dominant