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During a mean follow-up period of 22 ± 12months, 22 patients experienced cardiopulmonary events. In univariate analysis, %VC, TRPG, PVRecho, TRPG post 6MWT, and PVRecho post 6MWT were significantly associated with cardiopulmonary events. Multivariate analysis using the Cox proportional hazards model indicated that %VC [hazard ratio (HR) 0.97, p = 0.009] and PVRecho post 6MWT (HR 1.77, p = 0.004) were independent predictors of cardiopulmonary events in patients with ILD. In addition to parameters of pulmonary function tests, increased P