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Consequently, aberrant glycosylation could cause alteration of semen function and also sterility. Currently, mass spectrometry-based technologies have permitted large-scale profiling of glycans and glycoproteins in person semen. Quantitative analysis of semen glycosylation in addition has indicated numerous involved glycoproteome dilemmas in male sterility additionally the potential biomarkers for diagnosis of male infertility in clinical. This review summarizes the part of glycos