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Subjective symptom assessments were estimated lowlier than objective finding assessments. Dupilumab has a therapeutic effect on severe PAR in severe AD patients. Dupilumab has a therapeutic effect on severe PAR in severe AD patients.It has been reported in recent studies that restraint stress on pregnant mice during the preimplantation stage elevated corticotrophin-releasing hormone (CRH) and glucocorticoid levels in the serum and oviducts; furthermore, CRH and corticosterone (CORT) impacted preimplantation embryos indirectly by trigge