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How to Choose the Best ADHD Medication for Adults Stimulant medications like methylphenidate and amphetamine function by increasing and balancing levels of brain chemicals. Doctors often prescribe them as pills, liquids or patches. utilize drugs known as norepinephrine-reuptake inhibitors and alpha-2 agonists to treat ADHD. These medications are usually employed "off-label" as they are FDA-approved for a variety of ailments. Stimulants Stimulants are among the most commonly prescribed ADHD drugs. They increase the levels of brain chemicals dopamine and norepineph