2 week ago - Translate

https://www.selleckchem.com/products/r-hts-3.html
IgE production against innocuous food antigens can result in anaphylaxis, a severe life-threatening consequence of allergic reactions. The maintenance of IgE immunity is primarily facilitated by IgG memory B cells, as IgE memory B cells and IgE plasma cells are extremely scarce and short-lived, respectively. Our aim was to investigate the critical requirements for an IgE recall response in peanut allergy. We used a novel human PBMC culture platform, a mouse model of peanut allergy, and various experimental readouts to assess the IgE rec