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86, 95%CI 2.15-3.81], depressive symptoms (OR 2.16, 95%CI 1.39-3.35), alcohol use (OR 2.53, 95%CI 1.78-3.61) and non-suicidal self-harm (OR 1.35, 95%CI 1.09-1.67) was significantly higher in persistent unhealthy group. This study provided convincing evidence that unhealthy lifestyle trajectory during adolescence is associated with more than two-fold elevated odds for multiple domains of psychopathological outcomes over 5 years. This study provided convincing evidence that unhealthy lifestyle trajectory during adolescence is associated w