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Co-administration of ALA resulted in amelioration of the footprints of Ara-C induced toxicity in pregnant rats as well as the fetus. These findings indicate that the ALA supplementation offers protection against developmental toxicity caused by Ara-C prenatal exposure in rats. To verify antioxidant responses and lipid peroxidation can be used as sensitive indicators for the risk assessment of the Wei River. We investigate the effects of the Wei River on oxidative stress of planarian by antioxidant parameters, and use ICP-MS to measure th