https://www.selleckchem.com/pr....oducts/obeticholic-a
High-dimensional cytometry and unbiased computational analysis identified novel myeloid subsets recruited to the lung post-exposure driven by an influx of peripheral monocyte-derived progenitors. DEP and malathion, either alone or in combination, induced soluble mediators in bronchoalveolar lavage indicative of oxidative stress (PGF α), inflammation (LTB , TNFα, IL-12), and immunosuppression (IL-1, that were sustained or increased two weeks after exposures concluded. These findings indicate that macrophage accumulation and pu
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