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ADHD and Sleep Medication People suffering from ADHD have trouble sleeping. When they finally fall asleep they are agitated and awake frequently during the night. Actigraphy and polysomnography, which are both objective measures which show that children suffering from ADHD are more tired and have lower levels of sleep efficiency than their control counterparts. However the objective measures of sleep improve with MPH treatment. 1. Restlessness medication to calm the nerve