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The dependency when you look at the data due to repeated measures had been accounted for by an arbitrary intercept per person and an unstructured covariance R matrix was utilized as correlation construction. One more descriptive evaluation had been performed for 123 customers, for a complete of 375 12-month tests. A break point at age 7 years had been set when it comes to whole cohort and for SMA IIIA and IIIB. Age, SMA type, and ambulatory standing had been