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Medications For ADHD Stimulants are the most common medications for ADHD. They can be used quickly to improve focus and reduce impulsivity as well as hyperactivity. They can cause adverse effects such as stomach upset, headaches as well as changes in blood pressure and heart rate. The majority of stimulants are part of two groups of drugs: methylphenidates as well as amphetamines. They are available in liquid and chewable forms and are sold as short-acting and intermediate- or long-acting medications