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Single tracts, e.g., located in the cerebellum, remained nearly unaltered throughout the ages between 19 and 81 years. Conclusions Age corrections of diffusion properties should not be applied to all white matter regions and all age spans in the same way. Therefore, we propose three different approaches for age correction based on fiber tracking techniques, i.e., no correction for areas that do not experience age-related changes and two variants of an age correction depending on the age range of the cohort and the tracts considered.Alzh