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iffusion had become the main challenges for the sustainability of innovation in this sector. The future development depends on China's effort and ability to establish education and health research systems specific to medical devices.Background Caries in the dental pulp result in inflammation and damage to the pulp tissue. During inflammation of the pulp, various inflammatory mediators and growth factors are released, including IL-8, IL-10, TLR-2, VEGF and TGF-β through the NF-kB pathway. In the present study, therapy for pulpal caries