https://bms-986165inhibitor.co....m/elavl1-part-in-cel
A novel motif, the reverse BH3 (rBH3), has been confirmed to have interaction utilizing the anti-apoptotic Bcl-2 homolog MCL1 (Myeloid mobile leukemia 1) and now have been identified in the p53 homolog p73, together with CDK4/6 (cyclin dependent kinase 4/6) inhibitor p18INK4c, (p18, cyclin-dependent kinase 4 inhibitor c). To determine the conservation of rBH3 theme, we first evaluated preservation of MCL1's BH3 binding groove, where in fact the motif binds. We then constructed neighbor-joini
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