https://www.selleckchem.com/pr....oducts/icec0942-hydr
Rocuronium, a common neuromuscular blocking agent, is mainly excreted unchanged in urine (10-25%) and bile (70%). Age, sex, liver blood flow, smoking, medical conditions, and ethnic background can affect its pharmacological actions. However, reasons for the wide variation in rocuronium requirements are mostly unknown. We hypothesised that pharmacogenetic factors might explain part of the variation. One thousand women undergoing surgery for breast cancer were studied. Anaesthesia was maintained with propofol (50-100 μg
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