https://www.selleckchem.com/pr....oducts/Sapogenins-gl
Meropenem dosing for septic critically patients is difficult due to pathophysiological changes associated with sepsis as well as supportive symptomatic therapies. A prospective single-center study assessed whether fluid retention alters meropenem pharmacokinetics and the achievement of the pharmacokinetic/pharmacodynamic (PK/PD) targets for efficacy. Twenty-five septic ICU patients (19m, 6f) aged 32-86years with the mean APACHE II score of 20.2 (range 11-33), suffering mainly from perioperative intra-abdominal or respirato
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