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f this relatively inexpensive intervention will demonstrate whether an explicit effort to reduce the number of opioids prescribed results in a reduction in the amount of opioids consumed and help to inform future studies and guidelines. The NO PAin trial has been prospectively registered with clinicaltrials.gov ( NCT04566250 ). The NO PAin trial has been prospectively registered with clinicaltrials.gov ( NCT04566250 ). Pseudohypoaldosteronism type II (PHAII), also called Gordon syndrome, is a rare hereditary disease caused by variants in t