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Also, ovaries from mice lacking in HAS3 were stiffer contrasted to age-matched WT mice. Our outcomes demonstrate that the ovary becomes stiffer with age and therefore both collagen and HA matrices are adding systems regulating ovarian biomechanics. Notably, the age-associated upsurge in collagen and reduction in HA tend to be conserved when you look at the human ovary that will impact follicle development and oocyte quality.The goal of current study is to investigate whether Ferulic acid (FA
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