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These findings have implications for the understanding of the pathogenesis of this disease and the development of personalized medicine approaches. Charcoal-containing dentifrices are gaining popularity, but scientific information on their effect on oral health is scarce. This study investigated properties of dentifrices that may affect dentine abrasivity, as well as their ability to adsorb fluoride, their pH and the presence of harmful substances. The dentifrices NAO and COCO were subjected to the following analyses abrasivity, expressed