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https://www.selleckchem.com/pr....oducts/Dasatinib.htm
Objective Usage of tacrolimus is complicated by its narrow therapeutic index and wide between- and within-subject pharmacokinetic variability. We aimed to obtain more information regarding the influence of various covariates on the disposition of tacrolimus in the early phase after cardiac transplantation using a population pharmacokinetic method, and provide information for the individualisation of drug dosing in the clinical setting. Methods Routine therapeutic drug monitoring concentrations (897 observations) were retrospectively c